张巨峰
硕士生导师，博士，教授、广东省“千百十人才培养工程”校级培养对象。
近年来主持国家自然科学基金、广东省自然科学基金、广东省科技计划、中国博士后科学基金、深港创新圈计划、广东药学院博士启动基金项目。
担任国家自然科学基金通讯评议专家、广东省科技计划评审专家、深圳市科技创新委科技计划评审专家。
研究方向涉及腺病毒靶向性改造和可调控复制的研究、肿瘤相关基因鉴定和功能研究。
主要研究论文：
1.Zhang J, Wang D, Xiong J, Chen L, Huang J. MicroRNA-33a-5p suppresses growth of osteosarcoma cells and is downregulated in human osteosarcoma. Oncol Lett. 2015;10(4):2135-2141.
2.Zhang J, Luo X, Li H, Yue X, Deng L, Cui Y, Lu Y. MicroRNA-223 functions as an oncogene in human colorectal cancer cells. Oncol Rep. 2014 ;32(1):115-20
3.Zhang J, Luo X, Li H, Deng L, Wang Y. Genome-wide uncovering of STAT3-mediated miRNA expression profiles in colorectal cancer cell lines. Biomed Res Int. 2014:187105
4.Zhang J, Lu Y, Yue X, Li H, Luo X, Wang Y, Wang K, Wan J, MiR-124 Suppresses Growth of Human Colorectal Cancer by Inhibiting STAT3. PLoS One, 2013; 8 (8), e70300.
5.Zhang J, Wang Y, Zhen P, Luo X, Zhang C, Zhou L, Lu Y, Yang Y, Zhang W, Wan J. Genome-wide analysis of miRNA signature differentially expressed in doxorubicin-resistant and parental human hepatocellular carcinoma cell lines. PLoS One. 2013;8(1):e54111. doi: 10.1371/journal.pone.0054111.
6.Zhang J, Wei F, Wang H, Li H, Qiu W, Ren P, Chen X, Huang Q. A novel oncolytic adenovirus expressing Escherichia coli cytosine deaminase exhibits potent antitumor effect on human solid tumors. Cancer Biother Radiopharm. 2010 ;25(4):487-95.
7.Zhang J, Deng J, Zhang C, Lu Y, Liu L, Wu Q, Shao Y, Zhang J, Yang H, Yu B, Wan J.Association of GSTT1, GSTM1 and CYP1A1 polymorphisms with susceptibility to systemic lupus erythematosus in the Chinese population. Clin Chim Acta. 2010 ;411(11-12):878-81.
8.Zhang J, Wei F, Wang HP, Li HM, Qiu W, Ren PK, Chen XF, Huang Q. Potent anti-tumor activity of telomerase-dependent and HSV-TK armed oncolytic adenovirus for non-small cell lung cancer in vitro and in vivo. J Exp Clin Cancer Res. 2010 ;29:52-56.
9.Zhang J, Wang Z, Wei F, Qiu W, Zhang L, Huang Q. Computational modeling and functional analysis of Herpes simplex virus type-1 thymidine kinase and Escherichia coli cytosine deaminase fusion protein. Biochem Biophys Res Commun. 2007;360(1):46-50.